Probiotics are sold to us as a good gift; helps you to balance your bad types with bad ones; microbes that are camping in our camp. But a new test on mice has shown how their micro-organisms can grow to become attractive barriers, causing damage to the girl.
The news isn't very bad – we can use their ability to lift this gut meal in better bacteria.
“If we are going to use living things like medicines, we have to recognize that they are going to change, and that means what you are submitting into your body. And the thing you need is an hour after that, ”said a pathologist and a biomedical biologist Gautam Dantas.
Unlike other forms of recovery, livelihoods have their own life. Something you can swear can create. And what they can represent may alter.
"There is no microbial that protects evolution," said Dad.
Dr Victoria led a team of Washington University researchers who assessed a bacterium that had been marketed to help combat the diarrhea.
Just over 100 years ago, a German doctor named Alfred Nissle found some things Escherichia coli used for treatment of patients suffering from infectious diseases.
One particular battle is still standing out for its talent to try to fight the outdoors, especially in young children. E. coli Nissle 1917 (EcN) is proven to be a safe and effective remedy for what could be a killer disease.
To evaluate EcN's resilience after being swallowed, the mice team used to kill mice, which were specially born to be free from bugs.
The test topics were divided into four groups, each with a distinct micro-print. One of them was left entirely strange; the other three were given microbiomes showing different healthy and unhealthy states.
Each group has got together with EcN and then baited one of the following options – an old salt mouse mouse, more friendly use of mouse mice, foods mostly containing fat and sugar, and diet a rose that had a little root.
Five weeks later, the tracks were examined by the mouse. The happy people E. coli? He points out that they were not all as friendly as they were on their entrance, especially in a hurry to tackle a healthier diet.
Effects within the mice are a lot of western foods, EcN had made a collection that helped them cope with the weight and use those carcasses to hang around the length of the food. they expect.
These bacteria have also changed to become more glamorous, giving them a competitive advantage over the other residents.
More worry, the EcN within a group of mice which were treated by streptomycin had low levels of antibiotic protection.
"In a healthy context, of diversity, we haven't changed much, probably because it is Nissle's background," said Aura Ferreiro, a student in medical engineering.
"But you need to remember that we often don't use probiotics in people with a healthy microbial."
These actors were probably good news for the probiotic E. coli trying to make a home within their new environment but for their hospitality it is a great concern.
We do not make up with sticky bacterial cells that handle weight by easily adjusting carbohydrates.
The results show that probiotics are not the most popular kind of EcN, the kind of friendly guests we need in our homes, but are attackers of the space that we turn to if we don't treat the right amount of love. them.
Before we pass our germ pills forward artificially, there are a few things that you can keep in mind.
This is a mouse search. As we all know, there is a pile of mythology between these small mammals and people. It is a good step into your investigation that may require investigation, but it is not a case for immediately issuing a warning.
There is also something interesting about the study. The research team introduced a gene in to smother the amino-acid phenylalanine into their weight. E. coli Developed as a probiotic.
Some people have a condition called phenylketonuria which will stop them from breaking down properly in this block of building blocks themselves, and as a result can endanger its ability to cause brain damage.
By taking this probiotic to mice that are engineered by a similar situation that gave them temporary help to metabolize phenylalanine, reducing their levels by half. Inspections like this with other researchers already suggest that medical examinations are due to medical treatments for a number of situations.
The DNA of the EcN that was engineered was relatively stable over the week of treatment, suggesting that common probiotics could benefit from hand-help to turn them into small heroes of gut and chicken. at the same time to maintain their devotion.
“We can use the principles of evolution to develop better treatment for people who need it most. This is an opportunity, not a problem, "said Danny.
It is clear that probiotics have many potential for our health. We have to learn how to keep on our side.
This research was published Cell guest & microbobe.