Biologists have empowered emergency mosquitoes



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Laura Duvall et al. / Clach, 2019


American scientists were able to find the yellow-eyed food management method of yellow women. They found that a receptor 7 of the neuropeptide Y is similar, which governs its & # 39; desire in the human body, depends on the desire to & # 39; find blood in his body. With the help of the builder's builder, which, in particular, affects people, scientists have also reduced the food from women. Article published in the magazine CellSouth Westerly

Female mosquets that feed animal blood and humans, including healthy healthy breeding. After taking food, the woman will lay eggs, and she does not. looking for food for a certain time. At the same time, there is no good understanding of the device that allows its women to stop having a & # 39; Finding food and physical activity in her body during the breeding season.

Scientists under the leadership of Laura Duvall from the Rockefeller University decided to find out whether the leak and restraint are more likely to be done; Finding food from mosquitoes and other animals. For the work of oxygenic neurons (that is, food & nutrition) in many species (including people), the neuropeptide work Y is responsible: peptides are similar to which are associated with different receptors are also found in the mosquito brain. To find out how precise they were, researchers used a number of yellow yellow jewels (Aedes aegypti), which would either result in sheep's blood, or blood vessels (similar to the very combination of a human-rich, rich protein in a protein), or saline.

The mosquitoes gave their whole food but only true and artificial blood forced them to stop extra food and laying eggs: for three days after feeding, and when women were going to do it, fed with eggs of blood, they were not pulled by the man's hand and they did not bite. Mosquitoes would salt salt, and # 39; Doing another research for food in two days: biologists believe they had to eat food this time. Also, women from this group can not position eggs. It was expected that a & # 39; Children from the females who fed on artificial blood.

To find out if mosquitoes can control their taste by affecting neuropeptides similar to Y, develop special olfactometer scientists: they put the mosquitoes in a room where carbon two -Dext it out of a hole, which is a? mock mosquitoes when they find food. In front of this, 10 collectors and invaders associated with a neuropeptide Y were given to mosques, which are used to reduce or increase their food in humans: Variety of behavior with saline, and antagonists – with bloody blood that gave food to the women. The insecticide study was considered two days after eating a mixture.

Out of all drugs used, there were two guns and one receptor attack that had an impact on mosquitoes associated with neuropeptide Y. In particular, Take on behavioral devices that send Y2 and Y4 human receptors, preventing the distribution of Y neuropeptide and, thus, reducing habitat, mosquitoes did not try to find food for several days. The most effective method of food from Y2 drugs expanded to female makers.

To find the receptor, who are drugs that work on Y2 receptors, scientists have found 49 peptide receptors in vitro from the joint DNA mosque. The receptor's target is for the effective dispute of the receptor7 of the neuropeptide Y (NPLYR7), which is mosquitoes coded by a & # 39; gene NPLYR7Next To investigate the activity of this gabter in life, with scientists who use CRISPR-Cas9 mosquitoes with a disability gene NPLYR7: previously effective drug was no longer valid.

Finally, scientists of the NPLYR7 receptor multipurpose scientists have declared a lively unbalanced female mosquito. They got tightening mosquitoes successfully: people who were put in a cage with a living mouse drink less blood than the mosquets from the control group.

The bachelor of yellow fever is the behavioral of serious diseases, including yellow fever, dengue fever and Zika virus. In the process of eating blood live organisms, they can not be able to; Delivering discomfort except at risk. Successful recognition of a device that limits the predictions of mosquitoes, so they can not stop the search for food, but also spreading people who are allowed.

To limit the spread of virus spread viruses in other ways. For example, in the summer of last year, scientists have hampered dengue fever in a city in Australia by weakening ability to; virus in the muscles of yellow fever.

Elizaveta Ivtushok

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