A team led by researchers t
Spanish has been there for the first time in Mice
the extermination completely cancer of it pancreas, a movement that opens the way to effective cures against this body of bone, which has a very high death rate.
The team, led by Dr Mariano Barbacid, head of the AXA group of the National Center for Ornithology Research (CNIO), has achieved this search by removing two mollusc targets. T (known as EGFR and RA-RAF) related to the gene that is responsible for introducing more than 95% of this type of pressure (the KRAS oncogene).
The first step
Barbacid have been involved, in a media perspective, to publish the results, in the first "step", in which we need to continue exploring, where this kind of medicines will not be used. The average incidence of cancer is caused by having people in a term of at least five years, so it does not serve the patients who currently suffer from this type of cancer.
Pancreatic cancer, one of the most invasive species in the world, affects around 8,000 people in Spain each year, with a limit of 5 out of five years after. was judged.
Of the most enduring
The "ductal" pancreas "adenocarcinoma of the pancreas" is one of the largest cancer treatment cases at present, and at the moment its treatment is restricted to cases where local fur is very local. and it can be removed quickly, which represents less than 10 per cent of patients. t
In the USA this is the third cause of death, behind lung cancer and spinal cancer, and its death is higher than breast cancer in Spain.
"We are getting land to cancer" t
The research findings were revealed today to the media, as well as Barbacid, Dr David White. Alfredo Carrato, head of Oncology Service in Madora y Cajal Hospital in Madrid, and director of the research into the health of Ramón the Cajal; and Dr. Marta Puyol, Research Director of the Spanish Society for Cancer.
Dr. Carrato every day "that we benefit from cancer" but we are regretted "not a pancreatic cancer issue", called a "first-rate health crisis", and repentance criticism It is late and the lowest standard of attainment is low.
In the work, it was also proved that a ban on the two mountaineering targets hinders the multiplication of nine out of ten human pancreatic illness, although this progress has been confirmed by experimental modules. .
The authors of the research have explained that these treatments are not successful in proving patients, but this action is considered to be a necessary step in the development of clinical trials.
In Spain the number is 39; “average” pancreatic cancer like the rest of the world (around 6.6 cases per 100,000 people per year in men and 3.9 for women), but with a very significant increase in the last few decades.
The research has made use of a new generation of genetically modified mice to attract the same changes that are reliant on most types of human beings.
As a result, some tumors did not stop growing but in a few weeks disappeared, a therapist effect that had never been seen in any experimental module, and it was also found that this had gone. T achieving very low levels of toxicity (and easy control of dematitis).
Dr Carrato has been diagnosed as having "very late" pancreatic cancer, and has affected the importance of sweeping asymptomatic patients (when there is family history), personal treatment , and the need to focus resources on very specific centers.
“Our commitment is to land the disease; It is to be performed in our patients about the achievements of the Mariano Barbacid team already in mice, "said Alfredo Carrato.
Barbacid, who has said that the results of these people should be affected by "pancreatic cancer", should not discourage these results from cancer, that kicking cells are not a problem with cancer t but to fulfill it without high toxicity.
This resurgence has been achieved with "very little" poisoning, said Dr Barbacid, who showed that the results are opening to new drugs that allow them to "poison" that has to avoidance of usage. at present to fight the disease.
The challenge is to move from trying to try animals, according to Dr Carrato, who has decided that the pancreas is, although he is bruising. rare, the deadliest thing about everyone, and in 95% of cases is a diagnosis. He is "unlucky".