Dementia Senile: these risks have not been given to a large extent


Atlantic: A survey by the UK Alzheimer's Research Trust on 2361 UK citizens show that only 50% are capable of identifying a risk of risk that can dementia. Only 1% of respondents are able to recognize and prevent the 7 risk factors. What are they?

André Nieoullon: If it is a common identifier for many generic systems, it is a lack of knowledge in its name; public about what is established – if it is not considered – as a factor of a particular factor (mainly behavior nature). ), diseases that most of our well-known and widely-known citizens are broadly due to their knowledge through the media. For example, as a specialist in Parkinson's disease, I am always influencing the "mix" between Parkinson's disease and Alzheimer's disease, for example, when we are infected. ask the question that identifies one or two of these diseases. So, in terms of their "risk factors", there is no doubt that a survey that would be done in our country would be the same as the one you put in the United Kingdom, Similarly, in this regard, and this is important, for people who do not have a greater or lesser effect on their illness.

So we need to tell and know again, and this is our general responsibility, for you, the media, and for us, the researchers. The road is still long but if a gentleman needs to be & # 39; expressed as a result of its potential impact. The people who are developing because of this misunderstanding and the huge emergence are; to the public about these diseases. In fact, at the level of our knowledge at present, trying to avoid Alzheimer's illness, and usually dementia, such an incentive.

Despite recent recent work, especially in molluscan and genetic drugs, our misunderstanding continues to be the alzheimer's serious adhesive processes with the clinical & ; shows the vast diversity, and we believe that we do not treat "a" disease, but with bodies of closely related diseases, on the most different material, which is a & # 39; Guide experts to talk instead of dementias "Alzheimer's type". For example, as long as the most famous and most popular forms are & # 39; affecting people over 60-65 years, there are many forms, for example about 45, and related forms are clear. to the evangelical problems of the brain, what we can "dementia vascular". And the concept of "risk factoring" is not immediately accessible to everyone …

To do it, we will create an example of what is considered "the main risk of Alzheimer's disease", that is, the age of progression. When you write this, you need to know that the risk of a & # 39; Alzheimer's dementia enhances rising when you get older. Statistical data is, in fact, a specific number, and can be attributed to one-person scale. Emergency data shows that the older we receive, more likely we want to get this disease; and it is even possible to argue that the probability (as a statistical result) of the disease's development can be; reaching values ​​in the range of four people to 85 (this is a long life expectancy in France today for women), or even one in three after 90 years. Everyone agrees that this kind of danger can not be avoided and, in the situation what you can do, it's a great deal of death.

For a surplus, the data is not deeper and everyone can consider it completely without all the applications found here and there in this area. Scientificly, the causes of disease are only based on unusual genetic variations, and Alzheimer's disease, known as a "family", is one of the key features to be a starting point, which is a start 45 that is unlike the most common forms (what we & # 39; talk about here) called "idiopathic", which is means "no known purpose", later on. Therefore, family history can be careful to be a danger to the disease only if it is one of these rare forms with a genetic component based. In a careful way, however, it is introduced, if the disease of Alzheimer's particular disease (which represents only part of the dementia states that is considered like that .. .) The risk Alzheimer's disease has increased by 2 or 3 compared to the total population. So much for the most difficult elements, with scientific support.

In terms of the other risk factors that are considered to be able to make Alzheimer's disease possible, Most of them, the qualifying results that can only be attributed to equalities are more commonly reported than usual in the patient's experience. Pell-mêle, for the most advanced ones: a low level of education, how head injuries are as light as they are, and up to a given idea; Brief mention of the use in the kitchen of aluminum appliances! In fact, this does not mean that these incidents or behaviors are not involved in a dementia event, but, in any case, these are not the main factories … and the use of iron panels or Bac + 5 can not be a "protection" against their disease … Not to & # 39; Counting other types of potential hazards such as alcohol, smoking, high blood pressure or suffering from diabetes, which is definitely a major effect, not a & # 39; Most to Alzheimer's disease.

Despite that, a & # 39; We think we are obliged to prove clear differences in Alzheimer's disease among the dementia syndrome, just as we can not completely cure these diseases, , despite this, there is a real hope that Alzheimer's number of dementia cases, if they do not diminish, will not even change more, despite their life expectancy a & # 39; increasing numbers of people. This is to take into account the above-mentioned truth that, with most cases, Alzheimer's type dementia is related to the brain's brain problems. Therefore, better control of high blood pressure and metabolic disorders such as diabetes, may be at risk of reducing dementia by increasing the risk of diabetes. minimizing overlapping risk. There is nothing completely formal at this stage, but in line with some recent information, it is clear, where there is a care policy and the prevention of evangelical and metabolic risks, then the number of cases of dementia; increase further. As it stands, without any other type of idle; possible interventions to reduce the disease, it is possible to think as a real hope that you work effectively, although it is indirectly, on the disease. And in this regard it is possible that some anti-cholesterol drugs such as statins, or some anti-inflammatory medications, or some medications against the diabetes, may include an order sustainable corporations, useful strategies for combating some of the diseases of the disease, much more definitely than the proposal to accept such an antioxidant as it may be because it is how often promote … These reasons are a research purpose.

How to describe your knowledge of this disease and the degree of information about it? What do you think about dementia?

This has been mentioned above: in our state of knowledge we do not know anything about the causes and methods of psychosatics at Alzheimer's disease. This does not mean, indeed, that we are in full ignorance, but what I want to do; Consider here that our valuable information has so far but just in connection with the illness and that of others. So we were able to make sure that this participates or the cerebral area, participating in memory media such as the hippocampus, for example, or the intervention of unusual protein at molecular level; such as the known beta-amyloid protein, and tau protein, which is conglomerated in specific areas of the brain where neurons are dying. These basic detections have been constant for the time in which to implement drug healing despite hundreds of clinical trials. That's the truth. Dementia is unstable and certainly a healthy way of life seems to impede some of their shapes. But registration with Phrevert of these risk factors is still an exercise that can not be accessible to all. This is also why the media has a place in the education of the population, and in particular to be able to enter their right place by doing it; He gives a lot of confidence, usually with people who do not know them. And at this point I am thinking about the causes of the Alzheimer's Association of England Trust that it was not possible to investigate the product; cause it, for the reasons outlined above!

What impact does this information have?

If yes, as I have said, individual behavior has no direct effect on an illness or even an accidental event, we can only make a decision that the education of the population will have little impact on the number of cases new dementia, with most of the healthy lifestyles; leading to a reduction in cardiovascular factors. For this reason only, it is imperative to keep policies barrier in this area, and that may be an advantage of indirectly reducing dementia. My decision is then in my case to go to; requires public authorities to maintain this "reading" policy for the population, and Focusing on these cardiovascular and metabolic side effects (reduction of cardiovascular events, Stroke strokes, and metabolic disorders of diabetes), no requirement to set out goals that may be more advanced as reducing the number of problems, which are still more spectacular … But that does not; closing, naturally, that the day we bilingually will identify the factors that cause us; Alzheimer's disease outside the rare genetic movements, as long as they are not "avoided", so there are times for information campaigning this time stressed the illness. But, from my opinion, this time has not yet come.

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