Generation of a generation A Chinese scientist practiced much of his secret work


Shenzhen, China – The Chinese scientist who says that he helped to make hundreds of generations of genealogies in the world to maintain a traditional career, Retaining a lot of search confidentiality to find a larger focus – a & # 39; make history.

He began to implement Jiankui's ambitions in 2016, and later after a team of Chinese researchers. debate global debate with the statement that they had put on the DNA in the human laboratory. It's not long to put his mind on & # 39; pushing longer boundaries of medical habits.

The scientist trained in England, who was an Englishman, again gave an interest in a Stanford University consultant who was involved in a baby-born baby. He told The Associated Press last month that he had been working on the test for more than two years when he was hiding information from some of the medical staff involved in the research, as well as being like himself bosses.

He took advantage of the rules set out irregularly and generously available today in China, in some cases, swaming even local protocols and maybe laws.

"China's ambitious ambition, which is the desire to be the first one, has to crash with its desire to create and implement standards," said Jing-Bao Nie, a scientist of Chinese biology at the University of Otago in New Zealand.

On the afternoon of an international generating conference in Hong Kong this week, the 34-year-old scientist came out of the world by saying that he used the powerful CRISPR generating machine to change A DNA of bilingual girls born earlier this month. His claim can not be proven independently, and has not been published in a magazine, but he has drawn extremely rapidly from researchers and rulers.

Mainstream scientists in China and global scientists said the test should never have been.

"They selected a round of the whole process. They went a heroist," said Dr. Kiran Musunuru, genealogist of Pennsylvania University.

China's state television broadcaster, CCTV, said Tuesday could be inspected by the Ministry of Science and Technology, if the birth is confirmed.

His vocational career did not continue the planned script. He did not publish his / her most of his previous research about mice valuation and monkey DNA, Most scientists have done it. And as he went on with his most recent study, there were compelling conclusions about mystery and medical habits.

"If you're going to do something controversial and this is early, and if you want to be a leader of this move, you want to do it in an amazing way," said Dr. . Eric Topol, who is over the Scripps Research Translation Institute in California.

He was born in 1984 in southern China, who says his parents were his parents. At that time, the country just started to start; from Mao's remoteness, and average annual income was only $ 300. Phones were rare. Many towns were still tied by large roads.

First, he followed a common path for scientists about his generation. After graduating from the University of China's Science and Technology, he moved to the United States for degree checks.

There he got a Ph.D. in a biology from Rice University in 2010, and spent a year as a post-graduate researcher at Stanford. Stanford's consultant, Stephen Quake, said he was "very clear" and "at the forefront of trying to introduce new technologies into biology."

In 2012, he returned to China to take up a post at the University of Science and Technology – a group that was not released only a year earlier and is financed by the Shenzhen government, a well-known Chinese city for its technology companies.

"He was a keen interest in the gestation of human genome," and what situation would be appropriate, Quake said, remembers one of his walks. Earthquake gave feedback, but did not look at the survey.

It can not be conducted legally in the US or in the # 39; most of Europe.

China has prevented people from collating for replication. In 2003, its Ministry of Health provided guidance for the prevention of in-vitro clinics "clinical examinations that break moral or moral principles".

The young scientist saw this doubt as an opportunity. Sometimes researchers – Chinese or overseas – can not obtain funding or permission for non-ordinary projects in the US. or in Europe who receive financial support and openings in China.

Ren Xiaoping, a lawyer who aims to do the first human rehabilitation, has worked for many years in the US hospitals, but returned to China because he agreed his medical institution in Shenyang to support his research.

Guoping Feng, a neuroscientist scientist at the Massachusetts Institute of Technology, works with a research facility in the Guangdong department where its engineering engineers have engineered engineers to investigate similar identities of autism. China has fewer restrictions on labeling.

In 2016, he arrived at an AIDS advocacy group in Beijing to help him to investigate potential research partners – couples and his; trying to get children where HIV was HIV positive. There are already good ways to protect against a & # 39; gives AIDS virus in IVF. Instead, he had the aim of replacing DNA before being born to make children more likely to be able to; get HIV after birth.

Other scientists have examined similar breeding methods in a blade to prevent infections that are possessed, but not to survive.

For his CRISPR work, he did not ask for a prior permission from federal rulers. He listened to his survey in an online Chinese Chinese checks online on November 8 – long after he started.

It has the usual skills that many Chinese co-workers maintain.

For example, the laboratory did not give all medical staff information to directly help the expected pairs of the survey; including generating. They believed they were; Helps in general IVF attempts, with another degree of mapping on the genomes, without mental treatment, according to one of the experts involved in Qin Jinzhou's research.

Patient consent forms were uncertainly named as the "AIDS vaccine development" program.

He also asked for a committee from a nice committee outside the hospitals involved in the investigation. Lin Zhitong, the founder of the Women's and Children's Hospital, Shenzhen Harmonicare, told the AP in October that he had a hospital ethics committee councilor, but he had no other interest.

Information from medical staff has been accepted about generation of generations, as some doctors might have to agree to behave; Helping HIV positive couples, said Lin, who also said he did not work as a doctor or scientist, come from a family of hospital owner developers.

Driving or working around any survey partners is not the usual custom in China, "and spreads a wide-ranging spirit of informed consent," said Nie, the expert -eòlas. "In some cases, ethics committees are just rubber stamps."

After making an application, Harmonicare sent a statement to & # 39; reinforce human generation and identify research on any links with E.

Shenzhen expert released some of the results in YouTube videos. He did what he did in English, not a Chinese.

"He wanted to attract attention to the international community. Now he got what he wanted," said Nie.

His own university was held in the dark. The University of Science and Technology in South America said in a statement that he did not know about the work of E, and that he was "severely breaking out on mechanics and academic degrees."

His research team included former Rice Advisor, the physician professor Michael Deem, who is a sit on the scientific advisory board of two generating companies. Rice said he launched research on Deem's involvement.

In last month's interview at a & # 39; Shenzhen's workshop, he said that infants were essential in a generation. He wanted to be the first.

"Someone, somewhere, who does this," said he. "If not, I'm someone else."

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Follow Christina Larson on Twitter at South Westerly

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AP Chief Medical Writer Marilynn Marchione in Hong Kong, researcher Fu Ting and Emily Wang's video journalist in Beijing, added this report.

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The Press Associated series was made in partnership with the Howard Hughes Medical Institute of Science Institute of Education. The AP is accountable for all its content.

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