In human cells, knees work in a similar way to a gasoline in a car. The fuel they provide is the energy to work; although, reasonably, it must be spent in the right amount, or it can accumulate, causing a number of long-term diseases.
Now, if that cellular fuel was more likely to be used, at the same time? This is a team of researchers from Manchester University, AstraZeneca, Southampton University and the US National Institute of Health. In a survey, published today in March Nature's biologyshow how glucose can help in the treatment of lung diseases, from going to some common parasitic diseases in Asia and Africa.
Fuel for protection system
To carry out the audit, a team of scientists, led by a professor Andrew MacDonald, analysis of an area of special interest white blood cells: the macrophages. These cells are called "messages" of the defense system, because they are looking for and destroying pathogenic organisms and rubbish. And for this, as with other cells, they need to make that complex glucose. However, it is not in any amount. In fact, these researchers found the need for very special levels.
To prove exactly how the interactions between this carcase and the macrophages formed, they carried out a series of tests in the mouse, which they handled with it. interleukin-4 (IL-4). This is a protein generated by some cells of defense, that play non-aircraft work by the introduction of other parts of the immune system, such as the macrophages itself. But, mice with him problems involving or using glucose in cells of her lungs he did not answer properly as a presence IL-4.
Soon, glucose is essential for the recurring processes through which the immune system responds to pathogens. However, in some diseases, such as asthma, more dehydration causing the cells is caused, and that is why. block glucose receptors It may be useful to avoid this. Also, as he explained Collateral Dr McDonald, this is a strategy for the lungs and other members.
In the other case, the authors of the survey recommend that future generations of glucose may be controlled to fight against some lung diseases encouraging the action of the defense system. Reasonably, this does not mean that a "sugar skeleton" is beneficial first, because there are also no glucose and table sugar, and secondly it is it does a lot of research is still done in a controlled way. However, these decisions seem to mean that it is a fairly medium choice to carry out research.