They will find antibodies that are in place; protection of Andes hantavirus



Scientists from the University of Concepción, in Chile, have been protected against the impact of Andes hantavirus disease, who currently works in crimes, after being alone antibodies from people who survive the disease here.

This search could also be used for people, said Maria Inés Barría, microbiologist and co-ordinator of this research, which started in 2014 and has been published today's first findings in the Journal Translational Medicine magazine.

It is a disease in which; a hanta virus that gives people yards and subdivisions of the Andes, which are a? affecting the Patagonia Chilein and Argentinian area, the only one that has shown that people can also spread.

Andes hantavirus disease is produced in a very dangerous condition called cardiopulmonary hantavirus (SCPH) syndrome, causes fever, headache, low blood pressure and heart failure and lungs, and which is a major cause of high mortal levels.

The result of the investigation showed that antibodies were protected by those who persisted the animals from being able to; The SCPH suffered even when they were given after Andes hantavirus disease.

This suggests that they may be used as a medicine related medicine that currently has no remedies, according to the research.

"So far, there is no special cure for this disease, the only thing the doctor can be a supportive cure in the ICU," said Barria.

In 2017, there were 90 people arrested by the Andes hantavirus, and 24 were killed by SCPH.

The most vulnerable groups for this disease are people who live in rural areas or who work in agriculture or forestry areas and are higher in young men.

The search method of the search is to #; Outlining the antibodies of 27 patients who lived on the Andes hantavirus or showed a sharper signal.

The next step to be & # 39; removing hamsters with a fatal dose of the virus and then they gave them human antibodies, and in all they stopped the SCPH and survived.

"The hamsters were used because the model is similar to most people's syndication and psychology," Barria explained.

At the moment, the University of Concepción also develops dysfunction that is suited to humans and is thus able to prove in a clinical trial of these remote antibodies that were so successful in credits.

Also, once it has been confirmed that the method is; preventing the development of SCPH once Andes hantavirus exists, scientists want to investigate in a mice if it also works to prevent infection. virus.

"Our idea is to try it as a way of life with animals, to discharge a dose before the disease is taken, so we will increase the range of antibodies activity," said Barria, who It is hoped that products can be developed with this detection that prevents infections.

The expert said he could be a "short-term vaccine" because of his antibodies "people would be protected for a short time".

"Even if the protection lasts for three weeks or up to two months, it would be useful for the risk groups: forestry workers, agricultural workers, tourists who went to Patagonia or even to be hanta big harassment, "he said.

The researcher also noted that this finding could be a cure for other types of Hanna in Europe and Asia.

"The problem is not the technology, the request or the ideas, but the funding, which we need, to find out how far this research can go, "Barria decided. EFE

EFE


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