MIT researchers have created a device to create 3-D nanoscale objects near any shape. They can also make patterns of a variety of useful materials, including metal, quantum dots, and DNA.
"It's a way to send almost any type of material in a 3-D pattern with a jogged shape," said Edward Boyden, a professor of biological engineering and MIT brain and mental sciences.
Using the new approach, the researchers can create the shape and structure that they want to create; laser polymer scaffold patterns. After connecting other useful items to the scaffold, they will broadcast it, and # 39; Creating one-dimensional structures of the size of the source.
These bizarre structures could use applications in many areas, from optics to medicine to robotics, saying researchers. The methodology that uses many of the biological science sites and materials already makes it extensive for researchers who want to try it.
Boyden, who is also a member of MIT Media Lab, McGovern Institute for Brain Research, and Koch Institute for Alcohol Equality Research, is one of the oldest authors in the paper, which appears in the & # 39; question 13 of SciencePost-The-other other author, Adam Marblestone, is a research link with Media Media, and the main authors of his paper as graduating students Daniel Oran and Samuel Rodriques.
Creating a space device
Only the ways to create nanostructures are limited in what they can do. Scaffolding patterns can be on the surface of the construction light of 2-D structures but does not work for 3-D structures. It is possible that they create 3-D infrastructures by gradually increasing on top of each other, but this process is slow and challenging. And, as long as there are ways to print 3D-Diesel gaming products directly, they are restricted to specialized materials such as polymers and plastics, which do not have the necessary operational features for many requests. In addition, they can only generate self-supporting structures. (The procedure can produce a strong pyramid, for example, but not a tied tier or a weak range).
In order to overcome these constraints, Boyden and the students decided to modify their work for a few years ago for an elevated image of brain weaving. This method, known as amplification microscopy, incorporates machines into hydrogel and then extends it to, and # 39; allows advanced images with a regular microscope. Hundreds of research bodies in biology and medicines now use microscopy expansion, because it is a & n; Enables 3-D vision of cells with normal hardware.
By turning to & # 39; This process, the researchers found that they could create large-scale items that were set up in expanded hydrogen and then broadcast them to nanoscale, a method called "motivation implosion ".
As they did for an expanding microscopy, researchers used a very interesting polyacrylate material, which is often found in diapers, as the scaffold for the nanofabrication process. The scaffold is cleared in a solution that contains molecules of fluorescein, which is a Connect to the scaffold when laser light is applied.
Using a two photon microscopy, which allows detailed targets to be & # 39; deeply concentrated within the structure, researchers will be able to link fluorescence molecular to specific locations within the gel. Fluorescein molecules work as an acre to connect to other types of molecules that researchers can add.
"You have an acre connection where you want a light, and later you can insert anything you want to insert," said Boyden. "It may be a dot dot as much as it could be a piece of DNA, which could be a golden nanoparticle."
"It's a bit similar to film photography – a hidden image is created by showing sensitive material in gel for light. Then, you can make this fragile image become a good image by connecting other material, money, after that. Creating can create all types of structures, including levels, uninstalling structures, and complex patterns , "said Oran.
Once the molecules that are required are connected in the correct locations, the researchers will be able to; bend the whole structure by adding it to acid. The acid will block the negative costs in the polyacrylate gel so that they do not. Replicating each other again, causing the gel to be dangerous. Using a & # 39; This model allows researchers to circulate the 10 items per side (for a 1,000-minute reduction in volume). This capacity does not have a & # 39; Decline not only allows to make more adjustment, but also it is possible to collect material in a close-winged scaffold. This provides easy access for modification, and later the content will be changed; grow hard when it is spoiled.
"People have been trying to create a better tool to make smaller subjects for years, but we realized that if you use existing systems and store your products In this surrender, you can broadcast them down on the nanoscale, not to remove the patterns, "Rodriques says.
At this time, researchers can create objects that are about 1 cubic millimeters, with a resolution pattern of 50 nanometers. There is a trade between size and purpose: If the researchers want to do more things, about 1 cubic centimeters, they can achieve a resolution of about 500 nanometers. However, that arrangement could be improved by further developing its & # 39; process, says researchers.
Preferences are better
The MIT team is now searching for applications for this technology, and it's It is anticipated that some of the earliest applications may be in the eyes – for example, which can make specialized lenses to explore the basic features of the light. This way may also allow smaller, smaller lenses for applications such as cell phone, microscop, or endoscopes cell phones, which researchers say. Later in the future, researchers say that this approach could be used to build electrical devices or nanoscale devices.
"There are all kinds of things you can do with this," says Boyden. "Democrats can limit the boundary opening that we can not still think."
Many of the tools needed for this type of building are already. "With laser you can find it in many biology works already, you can scan a pattern, meatalan, semiconductors, or DNA, and then drop down," said Boyden.
Like this article? Click here to subscribe to free newsletters from the Lab Manager