Nuclear inflammation in the nose stimulates smell in human subjects


Boston, Mass – Physicians at Eye and Ear Massachusetts have been encouraging smell in humans. use nose electrode to prevent illness in the & n; olfactory, a structure in the brain where smell from the nose is handled and put into deeper parts of the brain. Reporting online today International Forum of Alarg & Rhinology, the research team describes their output, which is a. Provide proof of concept for attempts to improve implant technology to bring smell to those who have lost it.

"Our work shows that the idea of ​​smell refresh technology is to be good to analyze more," said the author, Eric Holbrook. , MD, Head of Department of Knowledge. Eye and Ear and professor of otolarynology at Harvard Medical School. "The development of cochlear implants, for example, did not accelerate quickly so that someone could put an electrotter in a patient's clad and he heard that the patient was often hearing some sort of type. "

5% of the general population seems to have smell loss or anosmia. Although some anosmia cases may be handled by basic cause care (often nasal barriers, where odors can not reach the -siostam olfactory due to diseases, polps or sinus disease), other causes that cause harm to the nerve-sensitive nerves (eg head injury, viruses and anomalies) are much more complex. There are no probationary remedies for these issues at present.

Our sense of smell not only contributes to our enjoyment of life, but also to our daily life and safety. We are responsible for our smell so that we are aware of the fog of fire prevention, natural gas reduction and the use of fireworks. avoiding bare food. In older people, there are estimates that more than 50% of the population over the age of 65 have experience of smell, it can be difficult to get proper nutrition, as a flavor awareness is closely linked to it; smell, and how taste is reduced, food reduces this population.

Implan Cochlear for the Strone

The work of researchers in the University of Virginia, Virginia, Massa Eye and Ear Medicine School at Commonwealth University has been stimulating work to address the & # 39; A question that the olfactory melodide's electric stimulation could be able to produce smell in human subjects.

The results are set out in the & # 39; International Forum of Alarg & Rhinology A report demonstrates this feasibility. In the report, researchers describe endoscopic procedures for the installation of engines in the sinus habitats of five patients with total smell potential. Three patients gave a description of smell (which included reports of antitheptic, eastern and fruity aromas), as a result of the stimulus.

This progress in a human patient who opens the door to "cochlear implantation for nose" can be improved – although the authors of the investigation Note that the olfactory inspiration concept is more challenging than the current technologies. The world's most successful neuroprostic device, cochlear implants have been on the market for more than three decades to encourage their listening audio to be heard in people with a huge hearing loss.

"We can do what we can do for these patients, and we hope we can finally re-greet in people with no smell," said Dr Holbrook. "Now we know that it can welcome electricity to the olfactory bomb – and that's exciting."


In addition to Dr. Holbrook, authors of the International Forum of Alarg & Rhinology include the first author of Sidharth V. Puram, MD, PhD, Washington University Medicine School, Reiner B. See, MD, and Aaron G. Tripp, from Massachusetts General Hospital, and Dinesh G. Nair, MD, from Brigham and Women's Hospital.

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Eye and Ear Massachusetts, founded in 1824, is an international center for medicine and research and teaching hospital in Harvard Medical School. A member of HealthCare Partners, Mass. Eye and Ear specializing in offthalmology (eye care) and otolaryngology-head and neck lab (ear care, nose and neck). Outdoor and Clinical clinicians provide care to & # 39; coming from the most modern to complexity. In addition, the world's largest audience and audio audiences, Mass. Eye and Ear have started new cures for blind, deaf and head and neck disease. Our scientists are guided by purpose to find out the basic biology under these conditions and to develop new healing and remedies. In the Best Hospitals Survey in 2018-2019, "US $ & World News rankings rated Mass. Eye and Ear # 4 in the country for eye care and # 6 for eye care, nose and neck. For more information about care and research that changes life at Mass. Eye and Ear, visit our blog, Focus, and continue Twitter and Facebook.

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