Radiative results of Mitochondrial DNA Exposure that may be given from the tuna


Not all DNAs are similar, and science has been a long time that not all DNA types have decreased from your mother and your father. But it seems that the time has come to transcribe the textbooks.

Although most of our DNA have a & # 39; living within a nucleus, some of our genetic code is stored inside mitochondria, the name & # 39; powerhouse of the cell. The normal vision of this mitochondrial DNA (or mtDNA) is exclusively from mothers, but new evidence suggests that it is not at all.

A new study is conducted by Taosheng Huang from Cincinnati Children's Hospital's medical center to show that human mitochondrial DNA can be protected from his father, in a particular situation that began to be done by a " A boy who is sick is treated.

The child, who showed signs, fever pain, and other symptoms, was evaluated by doctors, and was proven to have mitochondrial disorder.

When Huang runs the exams – and then they run again to be sure – he could not make sense of the results that came back.

"That's impossible," he said to NOVA Next.

The reason was Huang very Huang because the results of her boys were very bad. shows a combination – called heteroplasmic – a mitochondrial DNA, consisting of more than maternal donations.

Although there is evidence of spreading mtDNA to parents in other species, a debate on how the truth is in humans, but this has not been proven in this way.

"This develops genetically-based genetics," Trevor Branch eunologist from the University of Washington, who was not involved in the research, tweeted about the discovery.

When puppies showed evidence from the same heteroplasy, Huang and other mtDNA researchers of the mother's mother, who also showed the same mix.

This allowed the team to investigate the mtDNA of her / her parental parents, found that maternal mRNA was derived from a division of 60/40 depending on her mother and her father.

"Our conclusions suggest that, although the mother's mNAA medal lawyer is still valid, there are some specific cases where mtDNA may be given to those," the authors to & # 39; explained in their paper.

But although these issues may be independent, scientists do not expect to be as scarce.

In total, researchers identified three non-connected multi-generation families that showed a high degree of heteroplasm mtDNA – between 24 and 76% – over 17 individuals.

Previously, two separate case statements could be able to; early in the century suggest recommendations of mDNA notification, but for 16 years no other evidence appeared.

Now, we know that these products were not remote, and how advanced technology is becoming more advanced, it is more advanced; gives us a better tool to understand what's happening here and how the normal spread of human mRNA is true.

"This is a really exciting," said Xinnan Wang expert from Stanford University, who was not involved in the research, to NOVA Next.

"It may open a new new … and we will change how we look for a purpose [certain mitochondrial] diseases. "

The researchers say that it was the strength of the previous scenario – that there was a possible maternity supply – could have been done; meant that many of the two-cellular systems that meant that they were neglected as technical errors.

Do as possible, they are & # 39; recommends that the "clear and inspirational" evidence should now begin to take a broader assessment of the mtDNA options, which may result in maternal discharge. leaving the average.

"It is clear that these findings need to be taken into account with the fact that his / her maternal estate is still dependent on a longer timeframe and that his father's tragic symptoms seem to have in his father has been leaving a signal without finding a human genetic record, "the team is writing.

"Despite this, it is still an unprecedented opportunity in the field."

The results are reported PNASSouth Westerly

Source link