Scientists have developed in the USA to restore cartilage rehabilitation with osteoarthritis



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5 December 2018 – 16:45
Researchers at the Massachusetts Institute of Technology (MIT) in Cambridge, the United States, have developed a new experimental new anti-osteoarthritis drug intrusion into the divisional band and revived it.

Researchers at the Massachusetts Institute of Technology (MIT) in Cambridge, the United States, have developed a new experimental new anti-osteoarthritis drug intrusion into the divisional band and revived it. Ratio is tested in rats and is a step forward to achieve cure that improves the progress of this disease, where there is no cure.

Arthrosis includes a continued reduction of the artefacts' pages as a result of a & # 39; getting older or injured. This geography affects 300 million people worldwide and does not have any back, since the cartilage is a device that can not be revived.

Accordingly, patients can carry out jobs to introduce prothesis in the & # 39; connection that affects them or does not have a & # 39; cure medicine, so it's very difficult to get out on the side.

Most drugs are removed from the sections before they can affect them or can not enter inside the unit; side, where the cells that do it – than chondrocytes – are found, so they can not carry out their work.

The researchers led by MIT wanted a strategy to overcome this crash. They designed a nano-maker: a motorcycle that is the vehicle that is capable of getting within its & # 39; disease and drug addiction to chondrocytes. The bulk is made up of a sparkling part of which the drug is linked, similar structures with an electronic electric car and a form called PEG.

Because of its bad endeavors on the shore, the nanocarrier's positive taxes are causing a & # 39; stick to the device. PEG, on the other hand, allows him to have a & # 39; break through the bone and reach the chondrocytes.

According to La Vanguardia's newspaper, which will The publication of the Journal Translational Medicine journal, added the scientific science called IGF-1 to the nanocarrier, which encourages the " creating cartilage and lasting and running; grow chondrocytes.

In order to determine the strategy, they removed the nanocarrier with the drug into the knee of rats that were injured by osteoarthritis. Cure lets reduce cartilage, inflammation and appearance of bone changes related to osteoarthritis. Compared to the injection of IGF-1, the combination of the nanocarrier did not make much of the ten bills of the drug in the sections. In addition, this was maintained in effective assemblies in the chivalry for thirty-eight days, so it could be done. going completely weekday or enough.

Well: The Nation

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