The Chinese Scientist says that he is the first generation of babies: Shots


For the first time, a scientist says he has used a new powerful generation tool to change human beings genetically.

Scientist, He Jiankui from the University of Southern Science and Technology in Shenzen, China, says that he has used the human changes to be changed by the CRISPR generation system to do it; creating twin girls.

"Two beautiful Chinese girls mention Lulu and Nana has been crying to the world as healthy as any other children in recent weeks." He says in an online video. "The children are now home with their mother Grace and their father Mark."

He says his team had "gene genealogy" caused by sperm and eggs in their children to protect their children from the human immune virus (HIV) cause AIDS. The father of the HIV-positive children.

"When Lulu and Nana were just one cell, this surgery made a door through HIV being put in place to counter people," He says in the video, one of a few on the put online to protect and explain their work.

As the research has not yet been published in a scientific journal or carefully researched by other scientists, many researchers and biologists are still careful about the application.

However, if it is true, many said that the historical move, would be compared to the birth of Louise Brown, the first child that was created through in-vitro fertilizer, IVF.

"This event could be the same as Louise Brown in 1978," said George Church, a well-known Harvard genetic expert, by e-mail. "Both babies can enjoy a funny baby – but healthy," wrote the Church.

He and the Church are among hundreds of scientists gathering at the Second International Humanitarian Visit in Hong Kong. A roof was set out to try to reach a global consensus on whether it would be fair to be able to; change human beings by nature by CRISPR.

He says he has changed again that he has made a wide ranging review of attendees at his / her. top and elsewhere.

"This work is a breakdown from CRISPR-Cas9's careful and clear operation on a global scientific community for human shortcuts," said Jennifer Doudna, a biochemist at the University of California, Berkeley in an interview. Doudna helped CRISPR find and organized it. the summit.

"Everyone here at this conference is trying to check what was done and also if the process was done correctly. We still do not know, "said Jennifer Doudna.

But the application "reinforces the need to constrain the use of generations in human situations to situations where there is a clear and unmetable medical need and where there is no other approach, "said Doudna. She does not think that's the case in this situation.

"If this had been done to avoid HIV infection, there are other ways to prevent an already effective disease," Doudna says, as "washing" the sperm of a man on there are diseases to eliminate HIV.

"Why do you use this instead of an already established approach?" Doudna says.

For the investigation, he and his colleagues say that they used CRISPR to make changes in one-day embryo in a gene called CCR5. CCR5 gene generates HIV intake and intake; affecting the system of protection systems. Scientists have found many words to protect this route to protect people from HIV.

His team used CRISPR to prepare 16 embryos, and put 11 embryos prepared into women's women to try to make it stable before the wound was fulfilled, according to the Associated Press, which the first he said.

"No gene at any moment has moved to prevent HIV infection," he said. The friendly couple appear to be healthy, and they have been genetically analyzed. "It has proved that the gene work has worked safely," he said.

Nevetheless, other scientists bought if the workout was working hard, saying that it was too quick for the team to try the test.

"At this stage of technology is too long," wrote Shoukhrat Mitalipov, a science at the University of Oregon Health & Science at Portland, Ore. Mitalipov's B & B; The first scientist who used to use CRISPR to successfully organize human organization, but did not stop trying to use them to make infants.

Other experts agree.

"Although I value HIV risk to the world, at this stage, there are likely to be the dangers of & # 39 ; the preparation of installments for CCR5 can be more than the potential benefits, "wrote Feng Zhang, a MIT CRISPR beginner. Zhang noted that he would discharge a CCR5 gene "which means that a person is more than a virus in the western naval".

CRISPR enables scientists to make very precise changes in DNA easier than ever before. As a result, it revives scientific research and builds up highlights for major solutions, and including banning and dealing with many diseases.

But it has been a long time to think that human DNA may be altered that may have been declined for long generations. One reason is that a new disease error could be introduced which could be declined for generations. Another is that he could open the door to "baby illustrators" – children who are altered for non-medical reasons, such as being higher, stronger or clearer.

"If it is true, it has been said, then it is a very prompt and challenging test in making children change artfully," agrees Jeffrey Kahn, a biological expert at Johns Hopkins Berman Institute of Bioethics who is present at the top of Hong Kong.

But the development of CRISPR has encouraged some scientists to reconsider their exclusion for medical purposes. And researchers around the world have been running to find out how to do it safely. Many scientists believe it is unavoidable, but it should be restricted to non-choice situations.

"If this is true, this means trying to make an unhealthy and unhealthy test of human rights, and human rights abuse," said Marcy Darnovsky, active director of the Center for Genetics and Society, genetic behavioral group.

"Throwing to open the door to a society of genealogy and which impacts on our opportunities for a fair and just future," said Darnovsky.

He admits he is able to listen to criticism, but to defend the degree.

"I understand that my work will be controversial. But I believe families need this technology. And I want to criticize them," he said.

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