For the first time, a person living with HIV has given a kidney infection to an attacker who also lives with HIV. A multi-disciplinary team from Johns Hopkins Medicine completed the resurgence of HIV-to-HIV. 25. Doctors say that the donor and the recipient are doing well.
"This is the first time someone living with HIV will ever be allowed to pass on to the world, and that's great," said Dorry Segev, MD, PhD, doctor of medicine at Johns Hopkins University Medical School. “A disease that was a death in the 1980s has become so satisfying that those living with HIV are now able to save lives with a black gift – that's amazing. "
People living with HIV cannot yet give up tuberculosis as there were concerns about HIV as being a serious risk of renal disease in the donor. But research from Segev and recent colleagues has revealed more than 40,000 people living with HIV that the new antiretroviral drugs are safe for kidney, and that those with HIV still have the same risks. people are well-controlled and do not have HIV and are well enough to give kidneys.
"What is sensible about the first living black donor – who also lives with HIV – that this develops medication while struggling to get stigma, too. It's challenging to see HIV providers and the public otherwise, "said Christine Durand, MD, a professor of medicine and physiology and a member of Johns Hopkins wide Cancer Center Sidney Kimmel. “As waiting patients wait for us to be working with as many people as possible to save life as much as we can, we are they are hopeful. "
Durand and Segev manage HOPE in Action, an effort that includes many national inquiries into the feasibility, safety and effectiveness of HIV-to-HIV planning. This initiative was made possible by Segev's view on the HIV Organ Policy (HOPE Act) 2013 Act and a proposal for it. As well as leading the re-organization of HOPE who introduced the first US president in 2016, they are leading two tests for air transplantation and reintroduction. 'HIV-to-HIV from NIH. This is the first re-growth of black bulls in the next big milestone in HOPE.
"Don't phone me as a hero, first call me. I want to see who will come now."
Nina Martinez, the 35-year-old black donor living with HIV, learned the HOPE Act at the time of entering in 2013. However, until she saw a story line t On the medical drama Gray & Anatomy a few months later, she didn't realize that her own life would be cutting by giving black. The writers created Gray's Anatomy storyline about the first HIV-kidney donor, and Martinez saw her future potential.
“I have also been inspired by a friend and neighbor who has become a living black donor,” Martinez said: “I have a huge interest in clinical research being carried out and I have given my friend evidence to take care of her. having a lifeline to us, and by looking through me I knew if there was a way to help someone else, I had to do so under a research protocol it was very comfortable for me. "
Martinez lives in Atlanta and is a public health consultant, clinical research worker and policy adviser with the aim of eradicating the stigma that is still around HIV.
“Some people believe that people living with HIV are sick, & it's not right. or not looking good, 'said Martinez. “For me, I knew I was in good health. HIV was no longer a legal barrier to giving a gift, and I never thought HIV was a medical barrier. As a policy advocate, I want people to change what they believe about HIV. T I don't want to be a hero for anyone.
In July 2018, Martinez read on Facebook that a friend who was also diagnosed with HIV needed re-infection. Martinez was of the opinion that he would need to find a way to bring HOPE to her friend. She experienced her medical research and public health policy, contacted Johns Hopkins.
After communicating with Segev about the ability to provide, Martinez traveled to Baltimore in October 2018 to assess for a possible bloody donation at Johns Hopkins Hospital. The tests wanted a number of visits for analysis to ensure that it was fit enough to be given, which is normal in a black person assessment that might be possible.
But, before she was cleaned, her friend died. She sat in the funeral and considered her choices. Martinez decided, as she laments her friend, that she was still willing to donate to someone who would not know her now – anonymous.
"Despite the loss of my friend to kidney disease, I wanted to move on as a gift as a way of reverence," Martinez said. "I can do this for someone else, not because I'm special but because I'm strong. Other people living with HIV join me in clinical research to get them started." I've only lived but flourished, for my friend I was watching and all the people waiting for a resettlement. "
When they were assessing, the surgeon team confirmed that Martinez surgeons and low viral speed had healthy kidneys, which would meet essential criteria with the HOPE defense measures. After cleaning her, she successfully helped a recipient who wants to stay anonymous.
In the Journal of Transplant in 2018, surgeons explored the things that identifiers can be healthy enough to give a kidney. Those with HIV with good management, who do not have a history of diabetes, can have a high disorderly blood pressure or protein in their fort would be healthy enough to make a donation.
The doctors will continue to keep a close eye on the recipient and the donor. As a result of the new growth factors and the very effective antroroviral treatment options available, the team says they are hopeful of long-term HIV control and excellent black activity.
Around 113,000 people are listed as waiting in the USA for re-dispatch as in March 2019, according to the United Kingdom for the Sharing of Organs. Some 20 Americans die each day waiting for replanting; the longest re-cycling is for kidney. People living with HIV who want to live can save the lives of thousands of people living with HIV who need to be resettled each year.
Since the Johns Hopkins world reform in 2016, more than 50 funeral staff have died under the HOPE Act and more than 100 reprocessors under the HOPE protocol in the US.
Bottom: Johns Hopkins Medicine