The flu season is coming in: why does the WHO recommend quadrivalent vaccine t



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Each year, the start of autumn marks the start of a new race against the diseases that bring them the coldest seasons. And one of the worst is influenza, as a result of its impact on the most vulnerable groups of society (children, elderly people and people with past health conditions) and its quality of "mutar". each quarter and the impossible to control with a vaccine vaccine.

Worldwide there are between three and five million bad cases each year and between 250 and 500 thousand of them die in death. T. The same levels of influenza virus vary according to age: it is more prevalent in children (20/30%) and much lower in young adults (5/10%).

“The highest number of hospitals and hospitals caused by flu is seen in everyday life (over 65 years and under four years of age) and high rates are also recorded – as adults in patients and patients. T children – in some people with pre-conditions or comorbidities, such as pregnancy, renal illness, non-medicinal patients, etc. that cause a worse prognosis if the disease can be caused ". t Pablo Bonvehí is a member of the Commission for the Prevention of Infectious Diseases (SADI) Commission and at a meeting with journalists t The challenge of communicating in vaccines of these Infobae partly said: "There's a virus change in the virus as it multiplies and that this causes the virus to spread through time, so in general, you're not the same kind of flu each year. "

And after that, explain.virus containing two sub-tables (H1N1 and H3N2) t and within this, these changes will come, "he said:"In virus B it is not known as sub-bills, but we talk about local people and from 1985 we know that there are two connecting lines, t Yamagata and Victoria, which then suffers with some fluctuations but less than the A. viruses. "

During the 2018 season, the 2009 influenza H1 virus, similar to that found in vaccine vaccine, had the same B-Yamagata disease in the category B t introduction of a vaccine, although the line B Victoria was also encompassed the two rows B were surrounded"Bonvehí, who also said, said the virus A H3N2 was not completely connected to the vaccine."

The vaccine is being prepared based on the recommendations made by the previous World Health Organization (WHO) based on epidemiologic data collected on the last segments. “In most cases, the vaccine is linked to the virus which circulates, and in some cases it is smaller; The more the link between the virus that circulates and the virus is the most affected effect of the vaccine t“He explained the expert, at the meeting organized by the Argentine Society for Vaccination and Epidemiology (SAVE).

“In young adults the vaccine has a 70-90% effect to prevent influenza infection, in an adult over 65 years of age that flu is lower (in the influenza vaccine). The main aim of this group is to avoid problems, that the person will not get into flu and die from flu) – the development of Bonvehí and the children – the inspections t shown the effectiveness of a vaccine in pregnancy to prevent a child being ill in the first six months of life ".

In that regard, the medical practitioner and the president of the Argentine Association for Prevention and Immunization, said: "In defense people who cannot respond to the vaccine, as well as in a baby t too early that have less than 1,500 grams, which may have been immunized, is recommended as a coconut strategy, ie, the vaccine is given out close to the disease which could be threatened by this patient environment.

“From the hygiene perspective with the vaccines the State will provide, now from an individual perspective, everybody who wants less access to flu can have a vaccine,” he said.

From the first vaccination to today's recommendation

Flu vaccination has now started, and then became complex and then the bulls have been used extensively for a number of years. "Both of the words used are three-vaccine of the virus A and B. Bonvehi explained. From the end of 2012 and according to the cycles of both series B in the world, WHO assessed and recommended the inclusion of the ability to have quadrivalent vaccine, which incorporates both sub-sets A and both lines. B ".

The advantage of this new vaccine, which has been addressed by several countries as a priority, is that it "covers one of the same B lines, which this one does not include" .

“The way B virus B changes from year to year is more difficult to predict the A types. So WHO suggested that countries have quadrivalent vaccines, although they are maintaining the praise they have. , 'said the expert, who took that idea "We are in transition time, countries that are limited since last year.".

In Argentina, there will be quadrivalent available this year, although it is not yet in a big way. "The official calendar is the most common problem as last year," said Bonvehí, who stated that "the allowance allowed for the time is only allowed after three years in the country." he worked with the ANMAT to agree him after six months, ”he said.

Finally, Vizzotti remembers that every year a vaccine would be needed, particularly for two fundamental questions: t "Because the immunization given by the vaccine does not last longer than 12 months and because the viruses change".

“The challenge in a flu vaccine is huge because we need to create better vaccines,” said the expert. Unlike other diseases such as polio, flu cannot be eradicated because the natural disease does not protect the life, it is going down all the time, the vaccine is not 100% effective (you get at least the flu) and it is like a lake. various species such as pigs and birds.

In that sense, the aim is to reduce death and those at greater risk of dying, "said Vizzotti, for the people now" the challenge is to test the death. T Working to have a more consistent vaccine and persist We work on the standard vaccine, which even if it does not last a life, can be given, for example, every five years.

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