The Highlands of Scotland are full of stories about fairies, wolves and mysterious creatures about Loch Ness, but the true story is true. At Raigmore Hospital in Inverness, the capital of the area, they will still remember the day a 66-year-old woman came in through the door to retrieve her breast at one end from her toe. osteoarthritis. “You don't have to animate, as I don't feel the pain,” said the wife to the wizard, Devjit Srivastava, with a smile. He followed him, unbelievably, by the usual protocol and slept the patient, but he remained well. And if it was true?
And he was. An international team of researchers today provides Jo Cameron, a woman "compelling, happy, hopeful" and "unconsciousness of pain", a solution made to scientists by two mutations. T the gene that needs the same. exclude one-off cannabinoids in your brain. "It's fine. This makes them happy and I am happy with me. People like to be sad," as well as a Cameron joke.
“Often I burn in the kitchen and I don't know if it smells of burnt meat,” explained Jo Cameron t
After that work had to be painful, the anesthet Srivastava dismissed care for that woman. He noticed he got one dose of paracetamol, "perhaps with a standing course", and Cameron didn't ask more, he is still surprised. The doctor tried to take him out and nothing. The questions started.
A year earlier, Cameron had gone through another operation to put a prosthesis in place of his crook. He didn't feel pain, he said. “I often burn in the kitchen and I don't know it to have burnt meat. I have a lot of sites on my body, "he tells the phone." It's not a good thing. He has the advantages and disadvantages of it. The pain is warning you that something bad is happening. And I don't know. "
Srivastava warned other colleagues and this issue came to institutions such as the universities of Oxford, Cambridge and California. To be examined, published today in that special issue British Journal of Anesthesia, referring to the reasons why Jo Cameron is a delight to the heart. Each human cell works with a guidance manuscript of 3,000 million letters. A paragraph in that small book controls the making of the FAAH, the enzyme that causes anandamide, a chemical synthesis that then allows natural communication between neurons in the brain. The name anandamide comes from its awareness. Ananda, in Sanskrit, meaning happiness. It is regarded as a native cannabinoid as their effects similar to those of the cannabis plant, marijuana.
The researchers believe that Cameron gained two sides in the field of human genealogy required for the removal of the angels. “We believe there is no problem in giving pain, but that there is plenty of anemone in there. […] in the brain because of the genetic deficiencies, it doesn't feel the pain is, "summarizing Srivastava.
The anesthetist recalls that the body is putting electrical signals through the nerves to the back of the back, as put over the brain. "The signals that come into the brain." familiar with pain"But this sense depends on genetics, mental state, hormonal status, expectations, previous experiences and other factors," said Srivastava, and the natural soul of Cameron in Cameron could get that hard message in the brain. weakening.
“Our ultimate goal is to better cope with millions of people with religious pain,” said researcher James Cox.
"This is a remarkable story. It is one of the benefits for me to see a natural structure", which signals the murderer who ran into the case in a hospital in the Highlands of Scotland. Picture shows Srivastava and Cameron combined with the consultation. She looks to chew the hot blubber on the Scottish Scot, which is well known in some countries. fire balls. "Mrs Jo can eat them without any flavor," said the doctor with surprise.
“Our ultimate goal is to better cope with millions of people with religious pain,” said James Cox, the moilecular biologist in University College London and co-director of the research. is now working on the genetic modification of human cells in the laboratory to try to repeat Jo Cameron's assignments and understand their impacts.
Researchers recall that the route to new treatments will not be easy. Already in 2001, scientists from the United States showed that the genetically modified mouse had high levels of anandamide so that they could not create the FAAH enzyme, the material connected to happiness. However, recent clinical trials in relation to the FAAH protection contexts had failed. In 2016, one of these tests ended in France with five bad people, one of whom was a dead brain.
Despite all, Jo Cameron looks forward to the future. “There are a lot of people who feel a lot of pain. I would be delighted if my genetics help me to find a natural way to reduce their suffering, "he admits. He cannot. He hopes in the brain.