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Dismantling cancer & # 39; indicates weak spots



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Scientists have removed cancer to reflect their weaknesses, and find new ideas for healing.

A team at the Wellcome Sanger Institute disabled all genealogical teaching, at the same time, within 30 cancers.

It has thrown up 600 new cancer cancers and each one could be a drug target.

UK Cancer Research has praised the analysis of the survey.

Idea

The future study is looking into the future of personal cancer treatment. At the moment drugs such as chemotherapy cause damage through the body.

One of the researchers is Dr Fiona Behan, who died her second time after cancer of the cancer.

The first course consisted of a damaging heart on her mother's heart, so she was not physically strong for many second-time treatments.

Dr Behan told the BBC: "This is so important because we are currently dealing with cancer by treating the entire patient's body. We are not aiming for the cancer cells in particular.

“The information we have found in this survey has identified key weak areas of the cancer cells, and allows us to convert drugs into cancer and the healthy product to damage.”

Genetic reduction

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The researchers believe their work could lead to new treatments

Cancer is caused by mutations inside the cells of our own body to change the instructions written into our DNA.

Clans are contaminating cells that cause them to grow irregularly, spread all over their body and finally killing people.

The researchers started a gargantuan feat of separating all genetic teachings – called inner-gene cancer, to see what was necessary to survive.

They have targeted at least 20,000 of them in more than 300 tonnes of growth made from labels from 30 cancers.

They used a tool called Crispr – the only genetic technology used to re-engineer two children in China last year.

DNA is a very new, easy and cheap tool to treat DNA, and this study would have been a problem just ten years ago.

The results, published in Nature magazine, produced 6,000 essential species for at least one type of living cancer.

Some of these were not suitable for the development of cancer drugs, as they are also vital in healthy cells.

Others are already on the target of detailed drugs such as Herceptin in breast cancer – this team has identified it as a "confidentiality check" to confirm that the procedure is working.

Furthermore, it is longer than current science to develop suitable drugs, so the researchers have put down a short list of 600 possible new drugs for drugs.

Laser view

One target is "Werner syndrome RecQ helicase" which is also known as WRN.

The research team found that it was vital to keep some of the most unsustainable cancer.

WRN has a vital role in around 15% of cancer and 28% of breast cancer, but there are no controlled drugs.

The collaboration was undertaken by Sanger, the European Laboratory for Molecular Biology and GSK supermarkets. All results are publicly available.

The aim of the research is to develop a “Developing Independence Map” of all vulnerability of cancer.

Doctors could then confirm the patient's tumor and give them a cock of detailed drugs to kill the cancer cells.

Dr Behan told the BBC: "Did we understand what is happening in the cancer cells so we can fire our gun at cancer cells, not the whole body like it?" chemotherapy.

"This is the first step in adding a machine gun view."

Professor Karen Vousden, leading Cancer Research UK scientist, said: "What is doing is this powerful study, the scale.

“This work will provide some excellent starting points and the next step is to analyze the numbers identified as weaknesses in this study, in order to find out whether they are one day in the making. T continued development of new treatments for patients. "

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